Sumerianz Journal of Biotechnology

Online ISSN: 2617-3050
Print ISSN: 2617-3123

Quarterly Published (4 Issues Per Year)

Journal Website:


Volume 4 Issue 1 (2021)

Assessment of Some Heavy Metals in Two Species of Goby (Porogobius Schelegelii and Bathygobius Soporator) From Buguma Creek, Niger Delta

Authors : Wilfred–Ekprikpo P. C.
This study investigated the heavy metal concentrations in different organs such as gills, muscles, liver and gatro-intestinal tract (GIT) of two species of Goby: Porogobius schelegelii and Bathygobius soporator from Buguma Creek, Rivers State, Nigeria. The fish samples were collected from the creek and were preserved in ice chest box and transported to the laboratory for analysis. Samples were digested by using standard laboratory methods. The concentrations of metals were analyzed using a Varian AA240 Fast Sequential Flame Atomic Absorption Spectrophotometer (AAS). The Results obtained indicated that heavy metals such as Chromium (Cr), Lead (Pb), Zinc (Zn), Cadmium   (Cd), and Nickel (Ni) were significantly higher (p<0.05) in the liver of the two species than in the muscle, gills and the GIT. Comparatively, the concentrations of these metals were higher in the specie B.soporator than P. schelegelii in all the organs of the fishes under consideration. The heavy metal concentrations recorded in this study were above the limits recommended by Food and Agricultural Organization/ World Health Organization. The high concentration of heavy metals above permissible level suggests the need for caution during the consumption of these species from Buguma Creek due to health implications associated with heavy metals.

Pages: 46-51

Traditional Knowledge and Formulation of Medicinal Plants Used By the Herbal Practitioners in Puthia Upazila of Rajshahi District, Bangladesh

Authors : Most. Habiba Khatun ; A. H. M. Mahbubur Rahman
Traditional medicine has remained as the most affordable and early accessible source of treatment in the primary healthcare system of resource. Medical Practitioners are in Puthia Upazila of Rajshahi District of Bangladesh. The medical practitioners have a long history of traditional plant usage for medicinal purpose. The present research on Traditional knowledge and formulation on medicinal plant use by the medical practitioners in Puthia Upazila of Rajshahi district of Bangladesh was recorded. Frequent field trips were made during January 2018 to December 2018 to record medico-botanical data by interviewing medical practitioners of various age groups, mostly ranging between 20 to 76 years, including medicinal healers (herbalists/hakims). A total of 127 plant species under 105 genera of 66 families have been documented which are used for the treatment of 96 categories ailments. For each species scientific name, local name, habit, family, ailments to be treated, mode of treatment and part(s) used are provided. The phytochemical analysis and pharmacological investigations of traditional medicinally important plants by taking in view their proper conservation too, would help in developing novel drugs to treat ailments.

Pages: 22-45

Mineral Composition of Medicinal Plants Traditionally Used in the Management of Sickle Cell Disease in the Kwilu Province (Congo-Kinshasa)

Authors : J. M. Kitadi ; C. L. Inkoto ; E. M. Lengbiye ; D. S. T. Tshibangu ; D. D. Tshilanda ; K. N. Ngbolua ; M. Taba ; B. M. Mbala ; B. Schmitz ; J. L. Burubu ; P. T. Mpiana
The aim of this study was to determine the mineral composition of 10 plants especially Alchornea cordifolia, Alternanthera bettzickiana, Annona senegalensis, Cyttaranthus congolensis, Dissotis brazzae, Justicia secunda, Harungana madagascariensis, Hura crepitans, Hypoxis angustifolia and Vigna unguiculata used in the management of sickle cell disease by traditional practitioners in Kwilu Province. The Plants collection was done at Kwilu province, sample were evaluated through fluorescence spectrometric analysis. These plants were harvested in Kwilu province in the Democratic Republic of Congo The mineral composition analysis was carried out using the fluorescence spectrometric method. This study revealed presence of Twenty-three (23) mineral elements, in each of these plants among others: Potassium (K), Phosphorus (P), Calcium (Ca), Sodium (Na), Magnesium (Mg), Sulphur (S), Chlorine (Cl) and trace elements such as: Aluminum (Al), Silicon (Si), Vanadium (V), Chromium (Cr), Manganese (Mn), Iron (Fe), Nickel (Ni), Copper (Cu), Zinc (Zn), Selenium (Se), Bromine (Br), Molybdenum (Mo), Tin (Sn), Iodine (I), Barium (Ba) and Lead (Pb). Iron, Zinc (Zn), Selenium (Se), Copper (Cu), Calcium (Ca), Magnesium (Mg) and Manganese (Mn) are mineral elements that are related to sickle cell disease. Of all these elements, Potassium and Calcium were in a higher content while Lead, Tin, Bromine, Copper and Nickel are in trace amounts. The correlation coefficients obtained between the mineral elements are significant. The presence of some mineral elements like Fe, Zn, mg and Se can be useful for sickle cell disease patients.

Pages: 16-21

Near Complete Protection Against Covid-19 in a Section of Population: Implication of Lockdown on Development of Passive Vaccination to Counter SARS-CoV-2 Attack

Authors : Prabir Chakravarty Ph.D
COVID-19 is fast spreading around the globe in a highly contagious manner. Until date there are no therapeutic agents/vaccines developed which could control this highly infectious virus from spreading among human population. During early stage of COVID-19, stringent Lockdown was implemented throughout India on 25 March, 2020. Our earlier findings reflected that early introduction of complete Lockdown significantly controlled the spread of COVID-19 in the population immediately after Lockdown. It was hypothesized that immune response was responsible for the control of the spread of COVID-19. To further evaluate the role of immune response/passive vaccination, data from COVID-19 positive/recovered individuals in eight states were assessed for the month of December, 2020.  The results from our study reflect that in all the eight states, there was marked decrease in the number of confirmed COVID-19 cases after Lockdown, with one region recording no COVID-19 cases. All the states studied had very low number of active cases; the minimum number being two even after such a long period from the start of this disease. A negative correlation between number of recovered individuals and number of active cases of COVID-19 was noted. Here we hypothesize that passive immunization may have played a significant role in controlling SARS-CoV-2. It could be inferred from this study that implementation of prolonged Lockdown was able attenuate the virus and create an environment for the development of passive immunity in the section of population studied.

Pages: 8-15

Bioinorganic Membrane Using Kurumi, A New Liquid Crystal

Authors : Ricardo Gobato ; Alireza Heidari ; Abhijit Mitra
The work characterizes develop a single layer bioinorganic membrane using nano-molecule Kurumi C13H20BeLi2SeSi / C13H19BeLi2SeSi, is well characterize computationally. As its scientific name 3-lithio-3-(6-{3-selena-8-beryllatricyclo [,] oct-6-en-2-yl}hexyl)-1-sila-2-lithacyclopropane. The work was based on a molecular dynamics (MD) of 1ns, using the CHARMM22 force field, with step 0.001 ps. Calculations indicate that the final structure, arrangement have the tendency to form a single layer micellar structure, when molecular dynamics is performed with a single layer. However, when molecular dynamics were carried out in several layers, indicates the behavior of a liotropic nematic liquid crystal order. Kurumi features the structure polar-apolar-polar predominant. Limitations our study has so far been limited to computational simulation via quantum mechanics e molecular mechanics (QM/MM), an applied theory. Our results and calculations are compatible and with the theory of QM/MM, but their physical experimental verification depend on advanced techniques for their synthesis, obtaining laboratory for experimental biochemical. Going beyond imagination, the most innovative and challenging proposal of the work advances the construction of a structure compatible with the formation of a “new DNA”, based now on the kurumi molecule.

Pages: 4-7

Effects of Gongronema latifolium Leaf Extract on Malondialdehyde Concentration of Wistar Rats Administered With a Toxic Dose of Ibuprofen

Authors : Nnodim Johnkennedy ; Chinedu-Madu Jane Ugochi ; Nwaokoro Joakin Chidozie ; Bede-Ojimadu Onyinyechi Ogechi ; Ezekwesiri Cletus
Aim: To determine effects of Gongronema latifolium leaf extract on Malondialdehyde (MDA) levels of wistar rats induced by a toxic dose of Ibuprofen. Material and Methods: Thirty wistar rats were randomly divided into five groups with six rats in each group (n=6); Control (C) received normal feed only. T1 was administered with Gongronema latifolium leaf extract 50 mg/kg BW+ Ibuprofen, T2: Gongronema latifolium extract 100 mg/kg BW+ Ibuprofen, T3: Gongronema latifolium leaf extract 150 mg/kg BW+ Ibuprofen. T4: received Jbruprofen only.This lasted for fourteen days. On the 15th day, blood samples were collected and the level of MDA was then measured.  Results: T1, T2, T3 showed significantly decreased MDA levels when compared with theT4 at p < 0.05. Conclusion: Gongronema latifolium extract has an antioxidant effect on the prevention of elevated MDA levels.

Pages: 1-3