Sumerianz Journal of Scientific Research

    
Online ISSN: 2617-6955
Print ISSN: 2617-765X

Quarterly Published (4 Issues Per Year)

Journal Website: https://www.sumerianz.com/?ic=journal-home&journal=29

Archive

Volume 2 Issue 1 (2019)

Spectrophotometric Determination of Almotriptan Malate in Tablets Using Ammonium Molybdate and Phosphomolybdic Acid as Reagents

Authors : Buridi Kalyana Ramu ; M. Syam Bab
Abstract:
Two simple, sensitive visible spectrophotometric methods have been developed for the estimation of almotriptan malate either in pure or tablet dosage forms.  These methods are based on the precipitate /color formation by the reaction of drug with either reagents PMA-Co(II)-EDTA  at 840nm (Method A) or  ammonium molybdate-potassium thiocyanate in acid medium at 465nm (Method B).  Beer’s law obeyed in the concentration range of 16-48 µg/ml and 4-20 µg/ml for method A and method B respectively. No interference was observed from the usually existing additives in pharmaceutical formulations and the applicability of the method was examined by analyzing AXERT tablets containing AM. The statistical data indicates the accuracy, reproducibility and the precision of the proposed methods.

Pages: 12-17

Mathematical Derives of Evolutionary Algorithms for Multiple Criteria Decision Making

Authors : Tim Chen ; Hendri Daleanu ; J.C.-Y. Chen
Abstract:
In multiple criteria decision making (MCDM) with interval-valued belief distributions (IVBDs), individual IVBDs on multiple criteria are combined explicitly or implicitly to generate the expected utilities of alternatives which can be used to make decisions with the aid of decision rules. Optimization models are usually constructed to implement such combination. To analyze a MCDM problem with a large number of criteria and grades used to profile IVBDs, effective algorithms are required to find the solutions to the optimization models within a large feasible region. We anticipate experimental results will indicate that particle swarm optimization algorithm is the best one to combine individual IVBDs and generate the minimum and maximum expected utilities of alternatives among the four algorithms.

Pages: 5-11

A New Tool Preliminary Assessment on Temporal-Comorbidity Adjusted Risk of Emergency Readmission (T-CARER)

Authors : Tim Chen ; Hendri Daleanu ; J.C.-Y. Chen
Abstract:
Patients’ comorbidities, operations and complications can be associated with reduced long-term survival probability and increased healthcare utilisation. The aim of this research was to produce an adjusted case-mix model of comorbidity risk and develop a user-friendly toolkit to encourage public adaptation and incremental development. It has been shown in healthcare research that demographics, temporal dimensions, length-of-stay and time between admissions, can noticeably improve the statistical measures related to comorbidities. The proposed model incorporates temporal aspects, medical procedures, demographics, and admission details, as well as diagnoses. The research resulted in the development of Temporal-Comorbidity Adjusted Risk of Emergency Readmission (T-CARER) model using routinely collected hospital data.

Pages: 1-4